An animal's sex influences the effects of the excipient PEG 400 on the intestinal P‐gp protein and mRNA levels, which has implications for oral drug absorption
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.04.021
Abstract: &NA; There is a growing body of evidence which suggests that formerly regarded “inert” pharmaceutical excipients have the potential to influence oral drug bioavailability. The solubilizing agent polyethylene glycol 400 (PEG 400), for instance, has… read more here.
Keywords: protein mrna; oral drug; mrna levels; drug ... See more keywords
P.0564 Active suicidal ideation one year after the beginning of COVID-19 pandemic in a large spanish sample: risk and protective factors
Sign Up to like & getrecommendations! Published in 2021 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2021.10.533
Abstract: slight reduction in cell density of CA1/CA2/CA3 hippocampal areas (H&E staining). No differences in the cytoarchitectonics of cerebral cortex and thalamus were found. GC-related changes on the functional level was observed: a decrease in the… read more here.
Keywords: 0564 active; protein mrna; level; protein ... See more keywords
Bcl-2/Bax protein and mRNA expression in yak (Bos grunniens) placentomes.
Sign Up to like & getrecommendations! Published in 2017 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2017.07.045
Abstract: Placental function is complex and influenced by various factors; furthermore, it depends on a delicate balance between cell proliferation, cell differentiation, and cell death. Bcl-2 and Bax proteins are key apoptosis regulators and are considered… read more here.
Keywords: bax; protein mrna; bcl bax; yak ... See more keywords
Exploration of the effect of pulmonary fibrosis on erectile function in rats: A study based on bioinformatics and experimental research
Sign Up to like & getrecommendations! Published in 2021 at "Andrologia"
DOI: 10.1111/and.14085
Abstract: First, the bioinformatics database was used to predict the potential targets and signaling pathways of pulmonary fibrosis (PF) leading to erectile dysfunction (ED), and bleomycin sulfate was used to create a PF rat model. Then,… read more here.
Keywords: protein mrna; erectile function; expression; pulmonary fibrosis ... See more keywords
Effect of Qingguang'an II on expressions of OX42 protein and IL-1β mRNA of retinal microglia cells of rats with chronic high intraocular pressure.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2018.02.23
Abstract: The study investigated the effects of Qingguang'an II (a Chinese medicinal preparation) on expressions of OX42 protein and interleukin-1β (IL-1β) mRNA of retinal microglia cells of rats with chronic high intraocular pressure (IOP). SD rats… read more here.
Keywords: protein mrna; expressions ox42; chronic high; ox42 protein ... See more keywords
Combination of Small Extracellular Vesicle-Derived Annexin A2 Protein and mRNA as a Potential Predictive Biomarker for Chemotherapy Responsiveness in Aggressive Triple-Negative Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers15010212
Abstract: Simple Summary Triple-negative breast cancer (TNBC) is a highly aggressive disease. It is marked by a lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). Thus, treating TNBC… read more here.
Keywords: protein mrna; anxa2 protein; tnbc; chemotherapy ... See more keywords
In Cellulo Protein-mRNA Interaction Assay to Determine the Action of G-Quadruplex-Binding Molecules
Sign Up to like & getrecommendations! Published in 2018 at "Molecules"
DOI: 10.3390/molecules23123124
Abstract: Protein-RNA interactions (PRIs) control pivotal steps in RNA biogenesis, regulate multiple physiological and pathological cellular networks, and are emerging as important drug targets. However, targeting of specific protein-RNA interactions for therapeutic developments is still poorly… read more here.
Keywords: protein mrna; mrna interaction; cellulo protein; molecules cellulo ... See more keywords
Turmeric Extract (Curcuma longa) Mediates Anti-Oxidative Effects by Reduction of Nitric Oxide, iNOS Protein-, and mRNA-Synthesis in BV2 Microglial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27030784
Abstract: Plant-derived products have been used since the beginnings of human history to treat various pathological conditions. Practical experience as well as a growing body of research suggests the benefits of the use of turmeric (Curcuma… read more here.
Keywords: protein mrna; curcuma; curcuma longa; bv2 microglial ... See more keywords