Temporal changes in the accessory protein mutations of SARS‐CoV‐2 variants and their predicted structural and functional effects
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27964
Abstract: Emerging variants enable the continuous spread of SARS‐CoV‐2 in humans. The factors contributing to behavioral differences in variants remain elusive despite associations with several Spike protein mutations. Exploring accessory proteins may provide a wider understanding… read more here.
Keywords: functional effects; protein mutations; accessory protein; structural functional ... See more keywords
Sensitivity of two SARS-CoV-2 variants with spike protein mutations to neutralising antibodies
Sign Up to like & getrecommendations! Published in 2021 at "Virus Genes"
DOI: 10.1007/s11262-021-01871-8
Abstract: SARS-CoV-2 infections elicit a humoral immune response capable of neutralising the virus. However, multiple variants have emerged with mutations in the spike protein amongst others, the key target of neutralising antibodies. We evaluated the neutralising… read more here.
Keywords: protein mutations; sensitivity; spike protein; muc imb ... See more keywords
SARS-CoV-2 Spike Protein Mutations and Escape from Antibodies: A Computational Model of Epitope Loss in Variants of Concern
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.1c00857
Abstract: The SARS-CoV-2 spike (S) protein is exposed on the viral surface and is the first point of contact between the virus and the host. For these reasons it represents the prime target for Covid-19 vaccines.… read more here.
Keywords: protein mutations; cov spike; spike protein; sars cov ... See more keywords
Association between prognostic factors and the outcomes of patients infected with SARS-CoV-2 harboring multiple spike protein mutations
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-00459-4
Abstract: The outcome of SARS-CoV-2 infection is determined by multiple factors, including the viral, host genetics, age, and comorbidities. This study investigated the association between prognostic factors and disease outcomes of patients infected by SARS-CoV-2 with… read more here.
Keywords: protein mutations; outcomes patients; prognostic factors; association prognostic ... See more keywords