Computational prediction and redesign of aberrant protein oligomerization.
Sign Up to like & getrecommendations! Published in 2020 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2019.11.002
Abstract: Non-native intermolecular contacts often lead to aberrant protein oligomerization and aggregation. This phenomenon is behind the onset of several human disorders and is a bottleneck for the production of proteins of biotechnological interest. Intrinsically disordered… read more here.
Keywords: aggregation; aberrant protein; protein oligomerization; computational prediction ... See more keywords
Protein Oligomerization Based on Brønsted Acid Reaction
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DOI: 10.1021/acscatal.7b00272
Abstract: Oligomeric proteins are abundant in nature. However, their synthesis remains a significant challenge. A controlled oligomerization process can provide important insights into the evolution of modern proteins and the development of more efficient biocatalysts. Here,… read more here.
Keywords: protein; protein oligomerization; oligomerization based; gox ... See more keywords
Optimal fluorescent protein tags for quantifying protein oligomerization in living cells
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28858-0
Abstract: Fluorescence fluctuation spectroscopy has become a popular toolbox for non-disruptive analysis of molecular interactions in living cells. The quantification of protein oligomerization in the native cellular environment is highly relevant for a detailed understanding of… read more here.
Keywords: protein; protein oligomerization; fluorescent protein; optimal fluorescent ... See more keywords