Protein and pathway engineering for the biosynthesis of 5‐hydroxytryptophan in Escherichia coli
Sign Up to like & getrecommendations! Published in 2017 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201700064
Abstract: The hydroxylation of tryptophan is an important reaction in the biosynthesis of natural products. 5‐Hydroxytryptophan (5HTP) is not only an important compound for its pharmaceutical value but also because it is the precursor of other… read more here.
Keywords: engineering; biosynthesis; protein pathway; biosynthesis hydroxytryptophan ... See more keywords
Screening of the protein C pathway abnormality‐related thrombophilia by using thrombomodulin‐mediated tissue factor‐triggered clot waveform analysis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Haematology"
DOI: 10.1111/ejh.13777
Abstract: Absolute or relative protein (P)C pathway abnormalities (PC deficiency, PS deficiency, antiphospholipid syndrome (APS), factor (F)V‐abnormality, and high FVIII level) cause thrombophilia. Although screening assays for these thrombophilias are available, one utilizing clot waveform analysis… read more here.
Keywords: protein pathway; abnormality related; waveform analysis; clot waveform ... See more keywords
Plasma levels of protein C pathway proteins and brain magnetic resonance imaging volumes in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neurology"
DOI: 10.1111/ene.14058
Abstract: The involvement of protein C (PC) pathway components in multiple sclerosis (MS) has scarcely been explored. The aim was to investigate their levels in relation to clinical and neurodegenerative magnetic resonance imaging (MRI) outcomes in… read more here.
Keywords: protein pathway; multiple sclerosis; magnetic resonance; resonance imaging ... See more keywords
Modulation of the activated protein C pathway in severe haemophilia A patients: The effects of thrombomodulin and a factor V‐stabilizing fab
Sign Up to like & getrecommendations! Published in 2017 at "Haemophilia"
DOI: 10.1111/hae.13300
Abstract: The thrombomodulin (TM)/activated protein C (APC) system is a key regulator of haemostasis, limiting amplification and propagation of the formed blood clot to the injury site. Dampening APC's inhibition of factor V (FV) and factor… read more here.
Keywords: protein pathway; modulation activated; activated protein; pathway severe ... See more keywords
Ex Vivo Modeling of the PC (Protein C) Pathway Using Endothelial Cells and Plasma: A Personalized Approach
Sign Up to like & getrecommendations! Published in 2022 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.122.318433
Abstract: Background: The endothelial cell–dependent PC (protein C) pathway is critically involved in the regulation of coagulation, anti-inflammatory, and cytoprotective signaling. Its reactivity shows high interindividual variability, and it contributes to prothrombotic disorders, such as the… read more here.
Keywords: vivo; protein pathway; formation; apc ... See more keywords
The Bone Morphogenetic Protein Pathway: The Osteoclastic Perspective
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.586031
Abstract: Bone health crucially relies on constant bone remodeling and bone regeneration, both tightly controlled processes requiring bone formation and bone resorption. Plenty of evidence identifies bone morphogenetic proteins (BMP) as major players in osteoblast differentiation… read more here.
Keywords: protein pathway; osteoclastic perspective; pathway osteoclastic; bone ... See more keywords
Protein C Pathway in Paediatric and Neonatal Sepsis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2021.562495
Abstract: Protein C plays a major role in the physiological regulation of coagulation pathways through inactivation of factor Va, factor VIIIa, and plasminogen activator inhibitor. Protein C is involved in the control of inflammation during sepsis,… read more here.
Keywords: sepsis; paediatric neonatal; protein pathway; neonatal sepsis ... See more keywords
The screening and analysis of protein signatures and signaling associated with chemoresistance based on Protein Pathway Array technology in gastric cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology reports"
DOI: 10.3892/or.2017.6078
Abstract: The present study was aimed to identify proteins associated with signaling pathways involved in chemoresistance, and establish a predictive model for chemoresistance in gastric cancer patients after radical surgery. A total of 140 clinically-staged III gastric cancer… read more here.
Keywords: protein pathway; chemoresistance; gastric cancer; analysis ... See more keywords
Golgi-to-endosome Protein Pathway, Monkeypox and Malaria: Correspondence.
Sign Up to like & getrecommendations! Published in 2022 at "Turkiye parazitolojii dergisi"
DOI: 10.4274/tpd.galenos.2022.26818
Abstract: Anahtar Kelimeler: Golgi-endozom proteini, patika, maymun hastalığı, sıtma. read more here.
Keywords: malaria correspondence; endosome protein; pathway monkeypox; protein pathway ... See more keywords