hSSB1 phosphorylation is dynamically regulated by DNA-PK and PPP-family protein phosphatases.
Sign Up to like & getrecommendations! Published in 2017 at "DNA repair"
DOI: 10.1016/j.dnarep.2017.03.006
Abstract: The maintenance of genomic stability is essential for cellular viability and the prevention of diseases such as cancer. Human single-stranded DNA-binding protein 1 (hSSB1) is a protein with roles in the stabilisation and restart of… read more here.
Keywords: protein; protein phosphatases; dna; ppp family ... See more keywords
Protein phosphatases meet reactive oxygen species in plant signaling networks
Sign Up to like & getrecommendations! Published in 2019 at "Environmental and Experimental Botany"
DOI: 10.1016/j.envexpbot.2018.10.032
Abstract: Abstract The cellular redox state is vital for the survival of all living systems. The dynamic nature of reactive oxygen species (ROS) are reflected in their functioning both as a damage causal and control agent.… read more here.
Keywords: protein phosphatases; reactive oxygen; oxygen species; plant ... See more keywords
Mechanism of thienopyridone and iminothienopyridinedione inhibition of protein phosphatases.
Sign Up to like & getrecommendations! Published in 2019 at "MedChemComm"
DOI: 10.1039/c9md00175a
Abstract: Thienopyridone (TP) has been proposed as a selective inhibitor of phosphatases of regenerating liver (PRL or PTP4A). PRLs are dual specificity phosphatases that promote cancer progression and are attractive anticancer targets. TP and iminothienopyridinedione (ITP),… read more here.
Keywords: mechanism thienopyridone; protein phosphatases; thienopyridone; inhibition ... See more keywords
Comparative Analysis of Type 1 and Type Z Protein Phosphatases Reveals D615 as a Key Residue for Ppz1 Regulation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031327
Abstract: Type 1 Ser/Thr protein phosphatases are represented in all fungi by two enzymes, the ubiquitous PP1, with a conserved catalytic polypeptide (PP1c) and numerous regulatory subunits, and PPZ, with a C-terminal catalytic domain related to… read more here.
Keywords: protein phosphatases; comparative analysis; regulation; type ... See more keywords
The Calcium Chloride Responsive Type 2C Protein Phosphatases Play Synergistic Roles in Regulating MAPK Pathways in Magnaporthe oryzae
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8121287
Abstract: Reversible protein phosphorylation is essential in cellular signal transduction. The rice blast fungus Magnaporthe oryzae contains six putative type 2C protein phosphatases, namely MoPtc1, MoPtc2, MoPtc5, MoPtc6, MoPtc7, and MoPtc8. The major functions of MoPtc1… read more here.
Keywords: moptc1 moptc2; magnaporthe oryzae; protein phosphatases; protein ... See more keywords
Type 2C Protein Phosphatases MoPtc5 and MoPtc7 Are Crucial for Multiple Stress Tolerance, Conidiogenesis and Pathogenesis of Magnaporthe oryzae
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof9010001
Abstract: Protein kinases and phosphatases catalyze the phosphorylation and dephosphorylation of their protein substrates, respectively, and these are important mechanisms in cellular signal transduction. The rice blast fungus Magnaporthe oryzae possesses 6 protein phosphatases of type… read more here.
Keywords: magnaporthe oryzae; protein phosphatases; stress tolerance; moptc5 moptc7 ... See more keywords