Lymphocyte cytosolic protein 1 (L-plastin) I232F mutation impairs granulocytic proliferation and causes neutropenia
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DOI: 10.1182/bloodadvances.2021006398
Abstract: Key Points A missense mutation in LCP1, an actin-bundling protein, results in severe neutropenia, migration defects, and susceptibility to infection. LCP1 mutation causes actin dysregulation with increased F-actin, G2/M cell cycle arrest, dysplastic cells, and… read more here.
Keywords: lymphocyte cytosolic; protein plastin; i232f mutation; plastin i232f ... See more keywords