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   Articles with "protein polymer" as a keyword



Synthesis of Heterotelechelic Poly(N‐ethylglycine) Polymers: from Polypeptoid Lipid Conjugates to Protein‐Polymer Conjugates

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recommendations! Published in 2025 at "Macromolecular Rapid Communications"

DOI: 10.1002/marc.202500422

Abstract: The need for alternative hydrophilic polymers to polyethylene glycol (PEG) has intensified due to increasing concerns about immunogenicity and hypersensitivity reactions. In this work, we report the synthesis of well‐defined heterotelechelic poly‐N‐ethylglycine (pNEtGly) via acid‐catalyzed… read more here.

Keywords: heterotelechelic poly; protein polymer; polymer; lipid conjugates ... See more keywords

Self-assembled nanostructures from amphiphilic globular protein–polymer hybrids

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recommendations! Published in 2017 at "Polymer Bulletin"

DOI: 10.1007/s00289-017-2176-y

Abstract: Amphiphilic globular protein–polymer hybrids, consisting of poly(methyl methacrylate) (PMMA) as hydrophobic tail and globular protein as hydrophilic head, are prepared by the end-functional PMMA covalently binding to the primary amino groups of bovine serum albumin… read more here.

Keywords: protein; polymer hybrids; protein polymer; self assembled ... See more keywords
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A Thermally Reformable Protein Polymer

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recommendations! Published in 2020 at "Chem"

DOI: 10.1016/j.chempr.2020.09.020

Abstract: Summary Complex biomaterials easily formed by self-assembling proteins could transform regenerative medicine and 3D cell culture. However, although readily achieved by short peptides, materials assembled from proteins with a defined tertiary structure are still rare.… read more here.

Keywords: protein; medicine; thermally reformable; reformable protein ... See more keywords
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Targeting Multiple Binding Sites on Cholera Toxin B with Glycomimetic Polymers Promotes Formation of Protein-Polymer Aggregates.

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recommendations! Published in 2020 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.0c01122

Abstract: The canonical binding site on the B subunit of cholera toxin (CTB) binds to GM1 gangliosides on host cells. However, the recently dis-covered noncanonical binding site on CTB with affinity for fucosylated molecules has raised… read more here.

Keywords: cholera toxin; protein polymer; binding; binding sites ... See more keywords

Free-Standing Photocrosslinked Protein Polymer Hydrogels for Sustained Drug Release.

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recommendations! Published in 2021 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.0c01721

Abstract: The fabrication of protein hydrogels consisting of different properties and functional motifs is critical in the development of protein-based materials for biomedical applications. Here, we report the design and characterization of a triblock protein polymer,… read more here.

Keywords: protein; free standing; protein polymer; drug ... See more keywords

Rapid Oxygen-Tolerant Synthesis of Protein-Polymer Bioconjugates via Aqueous Copper-Mediated Polymerization.

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recommendations! Published in 2022 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.2c00726

Abstract: The synthesis of protein-polymer conjugates usually requires extensive and costly deoxygenation procedures, thus limiting their availability and potential applications. In this work, we report the ultrafast synthesis of polymer-protein bioconjugates in the absence of any… read more here.

Keywords: methodology; polymer; protein polymer; synthesis protein ... See more keywords

Protein-Polymer Conjugates as Biocompatible and Recyclable ATRP Catalysts.

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recommendations! Published in 2025 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.4c01342

Abstract: Atom transfer radical polymerization (ATRP) is a leading method for creating polymers with precise control over molecular weight, yet its reliance on metal catalysts limits its application in metal-sensitive and environmental contexts. Addressing these limitations,… read more here.

Keywords: atrp; polymer conjugates; recyclable atrp; protein polymer ... See more keywords

Intramolecular Interactions of Conjugated Polymers Mimic Molecular Chaperones to Stabilize Protein-Polymer Conjugates.

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recommendations! Published in 2018 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.8b00927

Abstract: The power and elegance of protein-polymer conjugates has solved many vexing problems for society. Rational design of these complex covalent hybrids depends on a deep understanding of how polymer physicochemical properties impact the conjugate structure-function-dynamic… read more here.

Keywords: interactions conjugated; polymer conjugates; conjugated polymers; protein polymer ... See more keywords

Improved Ordering in Low Molecular Weight Protein-Polymer Conjugates Through Oligomerization of the Protein Block.

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recommendations! Published in 2018 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.8b00928

Abstract: The self-assembly of protein-polymer conjugates incorporating oligomers of a small, engineered high-affinity binding protein, rcSso7d.SA, is studied to determine the effect of protein oligomerization on nanoscale ordering. Oligomerization enables a systematic increase in the protein… read more here.

Keywords: protein; block; polymer conjugates; oligomerization protein ... See more keywords

Charge-Preserving Atom Transfer Radical Polymerization Initiator Rescues the Lost Function of Negatively Charged Protein-Polymer Conjugates.

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recommendations! Published in 2019 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.9b00379

Abstract: When grown from the surface of proteins, negatively charged polymers cause irreversible inactivation, thereby limiting the breadth of the synthetic space that negatively charged protein-polymer conjugates can be applied to. More broadly speaking, independent of… read more here.

Keywords: negatively charged; charged protein; initiator; polymer conjugates ... See more keywords

Fully Oxygen-Tolerant Visible-Light-Induced ATRP of Acrylates in Water: Toward Synthesis of Protein-Polymer Hybrids

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recommendations! Published in 2023 at "Macromolecules"

DOI: 10.1021/acs.macromol.2c02537

Abstract: Over the last decade, photoinduced ATRP techniques have been developed to harness the energy of light to generate radicals. Most of these methods require the use of UV light to initiate polymerization. However, UV light… read more here.

Keywords: polymer hybrids; light induced; protein polymer; induced atrp ... See more keywords