Self-assembled nanostructures from amphiphilic globular protein–polymer hybrids
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Bulletin"
DOI: 10.1007/s00289-017-2176-y
Abstract: Amphiphilic globular protein–polymer hybrids, consisting of poly(methyl methacrylate) (PMMA) as hydrophobic tail and globular protein as hydrophilic head, are prepared by the end-functional PMMA covalently binding to the primary amino groups of bovine serum albumin… read more here.
Keywords: protein; polymer hybrids; protein polymer; self assembled ... See more keywords
A Thermally Reformable Protein Polymer
Sign Up to like & getrecommendations! Published in 2020 at "Chem"
DOI: 10.1016/j.chempr.2020.09.020
Abstract: Summary Complex biomaterials easily formed by self-assembling proteins could transform regenerative medicine and 3D cell culture. However, although readily achieved by short peptides, materials assembled from proteins with a defined tertiary structure are still rare.… read more here.
Keywords: protein; medicine; thermally reformable; reformable protein ... See more keywords
Targeting Multiple Binding Sites on Cholera Toxin B with Glycomimetic Polymers Promotes Formation of Protein-Polymer Aggregates.
Sign Up to like & getrecommendations! Published in 2020 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.0c01122
Abstract: The canonical binding site on the B subunit of cholera toxin (CTB) binds to GM1 gangliosides on host cells. However, the recently dis-covered noncanonical binding site on CTB with affinity for fucosylated molecules has raised… read more here.
Keywords: cholera toxin; protein polymer; binding; binding sites ... See more keywords
Free-Standing Photocrosslinked Protein Polymer Hydrogels for Sustained Drug Release.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.0c01721
Abstract: The fabrication of protein hydrogels consisting of different properties and functional motifs is critical in the development of protein-based materials for biomedical applications. Here, we report the design and characterization of a triblock protein polymer,… read more here.
Keywords: protein; free standing; protein polymer; drug ... See more keywords
Rapid Oxygen-Tolerant Synthesis of Protein-Polymer Bioconjugates via Aqueous Copper-Mediated Polymerization.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00726
Abstract: The synthesis of protein-polymer conjugates usually requires extensive and costly deoxygenation procedures, thus limiting their availability and potential applications. In this work, we report the ultrafast synthesis of polymer-protein bioconjugates in the absence of any… read more here.
Keywords: methodology; polymer; protein polymer; synthesis protein ... See more keywords
Intramolecular Interactions of Conjugated Polymers Mimic Molecular Chaperones to Stabilize Protein-Polymer Conjugates.
Sign Up to like & getrecommendations! Published in 2018 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.8b00927
Abstract: The power and elegance of protein-polymer conjugates has solved many vexing problems for society. Rational design of these complex covalent hybrids depends on a deep understanding of how polymer physicochemical properties impact the conjugate structure-function-dynamic… read more here.
Keywords: interactions conjugated; polymer conjugates; conjugated polymers; protein polymer ... See more keywords
Improved Ordering in Low Molecular Weight Protein-Polymer Conjugates Through Oligomerization of the Protein Block.
Sign Up to like & getrecommendations! Published in 2018 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.8b00928
Abstract: The self-assembly of protein-polymer conjugates incorporating oligomers of a small, engineered high-affinity binding protein, rcSso7d.SA, is studied to determine the effect of protein oligomerization on nanoscale ordering. Oligomerization enables a systematic increase in the protein… read more here.
Keywords: protein; block; polymer conjugates; oligomerization protein ... See more keywords
Charge-Preserving Atom Transfer Radical Polymerization Initiator Rescues the Lost Function of Negatively Charged Protein-Polymer Conjugates.
Sign Up to like & getrecommendations! Published in 2019 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.9b00379
Abstract: When grown from the surface of proteins, negatively charged polymers cause irreversible inactivation, thereby limiting the breadth of the synthetic space that negatively charged protein-polymer conjugates can be applied to. More broadly speaking, independent of… read more here.
Keywords: negatively charged; charged protein; initiator; polymer conjugates ... See more keywords
Fully Oxygen-Tolerant Visible-Light-Induced ATRP of Acrylates in Water: Toward Synthesis of Protein-Polymer Hybrids
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecules"
DOI: 10.1021/acs.macromol.2c02537
Abstract: Over the last decade, photoinduced ATRP techniques have been developed to harness the energy of light to generate radicals. Most of these methods require the use of UV light to initiate polymerization. However, UV light… read more here.
Keywords: polymer hybrids; light induced; protein polymer; induced atrp ... See more keywords
Nano-thin walled micro-compartments from transmembrane protein-polymer conjugates.
Sign Up to like & getrecommendations! Published in 2017 at "Soft matter"
DOI: 10.1039/c6sm02520j
Abstract: The high interfacial activity of protein-polymer conjugates has inspired their use as stabilizers for Pickering emulsions, resulting in many interesting applications such as synthesis of templated micro-compartments and protocells or vehicles for drug and gene… read more here.
Keywords: polymer conjugates; microscopy; protein polymer; micro compartments ... See more keywords
Determining electrospun morphology from the properties of protein-polymer solutions.
Sign Up to like & getrecommendations! Published in 2018 at "Soft matter"
DOI: 10.1039/c7sm02203d
Abstract: Integrating natural macromolecules, e.g. proteins, is a progressive trend in the fabrication of biocompatible sub-micrometer fibers with tunable diameters using the electrospinning technique. The correlation between solution properties and electrospun morphology is critical; it is… read more here.
Keywords: solution properties; polymer solutions; protein polymer; surface tension ... See more keywords