Designed protein multimerization and polymerization for functionalization of proteins
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Letters"
DOI: 10.1007/s10529-021-03217-8
Abstract: Multimeric and polymeric proteins are large biomacromolecules consisting of multiple protein molecules as their monomeric units, connected through covalent or non-covalent bonds. Genetic modification and post-translational modifications (PTMs) of proteins offer alternative strategies for designing… read more here.
Keywords: protein polymers; self assembly; genetic modification; reaction ... See more keywords
Convergence of Artificial Protein Polymers and Intrinsically Disordered Proteins.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.8b00056
Abstract: A flurry of research in recent years has revealed the molecular origins of many membraneless organelles to be the liquid phase separation of intrinsically disordered proteins (IDPs). Consequently, protein disorder has emerged as an important… read more here.
Keywords: protein; phase; protein polymers; phase behavior ... See more keywords
Engineering protein polymers of ultrahigh molecular weight via supramolecular polymerization: towards mimicking the giant muscle protein titin††Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02128k
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Science"
DOI: 10.1039/c9sc02128k
Abstract: Utilizing protein fragment reconstitution of a small protein GB1, we developed an efficient, supramolecular polymerization strategy to engineer protein polymers with ultrahigh molecular weight that mimic the giant muscle protein titin. read more here.
Keywords: protein; supramolecular polymerization; ultrahigh molecular; protein polymers ... See more keywords
Microbial Synthesis of High-Molecular-Weight, Highly Repetitive Protein Polymers
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24076416
Abstract: High molecular weight (MW), highly repetitive protein polymers are attractive candidates to replace petroleum-derived materials as these protein-based materials (PBMs) are renewable, biodegradable, and have outstanding mechanical properties. However, their high MW and highly repetitive… read more here.
Keywords: highly repetitive; weight highly; repetitive protein; protein polymers ... See more keywords