Partial rescue of F508del‐cystic fibrosis transmembrane conductance regulator channel gating with modest improvement of protein processing, but not stability, by a dual‐acting small molecule
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DOI: 10.1111/bph.14141
Abstract: Rescue of F508del‐cystic fibrosis (CF) transmembrane conductance regulator (CFTR), the most common CF mutation, requires small molecules that overcome protein processing, stability and channel gating defects. Here, we investigate F508del‐CFTR rescue by CFFT‐004, a small… read more here.
Keywords: protein processing; rescue f508del; channel gating;
Effect of Dietary Protein and Processing on Gut Microbiota—A Systematic Review
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DOI: 10.3390/nu14030453
Abstract: The effect of diet on the composition of gut microbiota and the consequent impact on disease risk have been of expanding interest. The present review focuses on current insights of changes associated with dietary protein-induced… read more here.
Keywords: gut microbiota; protein processing; effect dietary; protein ... See more keywords