SELYMATRA: A Web Application for Protein Profiling Analysis of Mass Spectra.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2249
Abstract: Surface Enhanced Laser Desorption/Ionization-Time Of Flight (SELDI-TOF) Mass Spectrometry is a variant of the MALDI. It is used in many cases especially for the analysis of protein profiling and for preliminary screening of biomarkers in… read more here.
Keywords: mass spectra; mass; analysis mass; web application ... See more keywords
Differently Tagged Probes for Protein Profiling of Mitochondria
Sign Up to like & getrecommendations! Published in 2019 at "ChemBioChem"
DOI: 10.1002/cbic.201800735
Abstract: The mitochondrion is one of the most important organelles in the eukaryotic cell. Characterization of the mitochondrial proteome is a prerequisite for understanding its cellular functions at the molecular level. Here we report a proteomics… read more here.
Keywords: probes protein; tagged probes; protein profiling; mitochondrion ... See more keywords
Photocontrollable Probes for Mitochondrial Protein Profiling
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200066
Abstract: The mitochondrion is the core site of cell signaling, energy metabolism and biosynthesis. Here, taking advantage of activity‐based probes, we synthesized two photocontrollable probes (YGH‐1 and YGH‐2), composed of a mitochondrial localization moiety “triphenylphosphonium”, a… read more here.
Keywords: probes mitochondrial; mitochondrial protein; protein profiling; photocontrollable probes ... See more keywords
(Glycan Binding) Activity-Based Protein Profiling in Cells Enabled by Mass Spectrometry-Based Proteomics
Sign Up to like & getrecommendations! Published in 2023 at "Israel journal of chemistry"
DOI: 10.1002/ijch.202200097
Abstract: The presence of glycan modifications at the cell surface and other locales positions them as key regulators of cell recognition and function. However, due to the complexity of glycosylation, the annotation of which proteins bear… read more here.
Keywords: glycan binding; mass spectrometry; activity based; based protein ... See more keywords
Activity-based protein profiling - finding general solutions to specific problems.
Sign Up to like & getrecommendations! Published in 2023 at "Israel journal of chemistry"
DOI: 10.1002/ijch.202300029
Abstract: In this retrospective/perspective, I will share thoughts on developing and applying the activity-based protein profiling (ABPP) technology, an endeavor that has consumed much of our lab's attention over our 25+ year existence. Before doing so,… read more here.
Keywords: profiling finding; protein profiling; activity based; based protein ... See more keywords
Activity-Based Protein Profiling of Non-ribosomal Peptide Synthetases.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2018_133
Abstract: Non-ribosomal peptide (NRP) natural products are one of the most promising resources for drug discovery and development because of their wide-ranging of therapeutic potential, and their behavior as virulence factors and signaling molecules. The NRPs… read more here.
Keywords: ribosomal peptide; based protein; nrps machinery; activity based ... See more keywords
Dried Blood-Based Protein Profiling Using Antibody Arrays.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1064-0_16
Abstract: Dried blood samples have been increasingly considered for clinical applications in recent years. The main disadvantages that limit DBS utility in clinical applications are the small sample volume collected, area bias and homogeneity issues, and… read more here.
Keywords: based protein; dried blood; profiling using; blood ... See more keywords
Artificial Intelligence-Based Prediction of Covid-19 Severity on the Results of Protein Profiling
Sign Up to like & getrecommendations! Published in 2021 at "Computer Methods and Programs in Biomedicine"
DOI: 10.1016/j.cmpb.2021.105996
Abstract: Background COVID-19 progresses slowly and negatively affects many people. However, mild to moderate symptoms develop in most infected people, who recover without hospitalization. Therefore, the development of early diagnosis and treatment strategies is essential. One… read more here.
Keywords: covid; severity; protein profiling; artificial intelligence ... See more keywords
Longitudinal plasma protein profiling of newly diagnosed type 2 diabetes
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DOI: 10.1016/j.ebiom.2020.103147
Abstract: Background Comprehensive proteomics profiling may offer new insights into the dysregulated metabolic milieu of type 2 diabetes, and in the future, serve as a useful tool for personalized medicine. This calls for a better understanding… read more here.
Keywords: protein; plasma; newly diagnosed; type diabetes ... See more keywords
MALDI-TOF MS protein profiling for the rapid identification of Chagas disease triatomine vectors and application to the triatomine fauna of French Guiana – CORRIGENDUM
Sign Up to like & getrecommendations! Published in 2017 at "Parasitology"
DOI: 10.1017/s0031182017001743
Abstract: Laroche, M., Bérenger, J.-M., Gazelle, G., Blanchet, D., Raoult, D. and Parola, P. MALDI-TOFMS protein profiling for the rapid identification of Chagas disease triatomine vectors and application to the triatomine fauna of French Guiana. Parasitology.… read more here.
Keywords: parasitology; identification chagas; protein profiling; rapid identification ... See more keywords
Quantitative Chemoproteomic Profiling of Targets of Au(I) Complexes by Competitive Activity-Based Protein Profiling.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00080
Abstract: Owing to the encouraging pharmacological action and acceptable toxicity profile, Au(I) complexes have attracted growing interest in the application of disease treatment. In order to investigate their potential target proteins and related bioinformation, herein, we… read more here.
Keywords: competitive activity; target proteins; activity based; based protein ... See more keywords