RPB5‐Mediating Protein Promotes Cholangiocarcinoma Tumorigenesis and Drug Resistance by Competing With NRF2 for KEAP1 Binding
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30962
Abstract: Cancer cell survival depends on the balance between reactive oxygen species production and scavenging, which is regulated primarily by NRF2 during tumorigenesis. Here, we demonstrate that deletion of RBP5‐mediating protein (RMP) in an autonomous mouse… read more here.
Keywords: mediating protein; tumorigenesis; rpb5 mediating; promotes cholangiocarcinoma ... See more keywords
Rab22a-NeoF1 fusion protein promotes osteosarcoma lung metastasis through its secretion into exosomes
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DOI: 10.1038/s41392-020-00414-1
Abstract: It remains unknown for decades how some of the therapeutic fusion proteins positive in a small percentage of cancer cells account for patient outcome. Here, we report that osteosarcoma Rab22a-NeoF1 fusion protein, together with its… read more here.
Keywords: neof1 fusion; rab22a neof1; fusion; fusion protein ... See more keywords
Ceramide kinase‐like protein promotes cutaneous squamous cell carcinoma
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DOI: 10.1111/bjd.20442
Abstract: Linked Article: Meyer et al. Br J Dermatol 2021; 185:147–152 . read more here.
Keywords: kinase like; like protein; ceramide kinase; promotes cutaneous ... See more keywords