Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors.
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DOI: 10.1016/j.ejmech.2020.112402
Abstract: Tuberculosis remains the most deadly infectious disease worldwide due to the emergence of drug-resistant strains of Mycobacterium tuberculosis. Hence, there is a great need for more efficient treatment regimens. Herein, we carried out rational molecular… read more here.
Keywords: carrier protein; protein reductase; acyl carrier; tuberculosis ... See more keywords