Oxysterol-binding protein-related protein 1 variants have opposing cholesterol transport activities from the endolysosomes
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e19-12-0697
Abstract: OSBPL1 encodes the full-length oxysterol-binding protein-related protein ORP1L, which transports LDL-derived cholesterol at membrane contacts between the late endosomes/lysosomes (LEL) and the endoplasmic reticulum (ER). OSBPL1 also encodes the truncated variant ORP1S that contains only… read more here.
Keywords: protein related; oxysterol binding; orp1 null; cholesterol ... See more keywords
Fungal oxysterol-binding protein-related proteins promote pathogen virulence and activate plant immunity.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of experimental botany"
DOI: 10.1093/jxb/erab530
Abstract: Oxysterol-binding protein-related proteins (ORPs) are a conserved class of lipid transfer proteins that are closely involved in multiple cellular processes in eukaryotes but their roles in plant-pathogen interactions are mostly unknown. We showed that transient… read more here.
Keywords: protein related; virulence; binding protein; oxysterol binding ... See more keywords
Platelet Protein-Related Abnormalities in Response to Acute Hypoglycemia in Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.651009
Abstract: Introduction Patients with severe COVID-19 infections have coagulation abnormalities indicative of a hypercoagulable state, with thromboembolic complications and increased mortality. Platelets are recognized as mediators of inflammation, releasing proinflammatory and prothrombotic factors, and are hyperactivated… read more here.
Keywords: protein; platelet protein; protein related; related abnormalities ... See more keywords
A Novel Secreted Protein-Related Gene Signature Predicts Overall Survival and Is Associated With Tumor Immunity in Patients With Lung Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.870328
Abstract: Secreted proteins are important proteins in the human proteome, accounting for approximately one-tenth of the proteome. However, the prognostic value of secreted protein-related genes has not been comprehensively explored in lung adenocarcinoma (LUAD). In this… read more here.
Keywords: secreted protein; overall survival; lung adenocarcinoma; protein related ... See more keywords
Illustrating the biological functions and diagnostic value of transmembrane protein family members in glioma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1145676
Abstract: Background It is well-established that patients with glioma have a poor prognosis. Although the past few decades have witnessed unprecedented medical advances, the 5-year survival remains dismally low. Objective This study aims to investigate the… read more here.
Keywords: protein related; transmembrane protein; prognosis; glioma ... See more keywords
Protein-Related Dietary Parameters and Frailty Status in Older Community-Dwellers across Different Frailty Instruments
Sign Up to like & getrecommendations! Published in 2020 at "Nutrients"
DOI: 10.3390/nu12020508
Abstract: The present study investigated the associations between frailty status and (a) daily protein intake, (b) daily body weight-adjusted protein intake, (c) branched-chain amino acid (BCAA) consumption, (d) evenness of protein distribution across main meals, (e)… read more here.
Keywords: protein related; frailty; related dietary; frailty status ... See more keywords