A Multimodal Protein Representation Framework for Quantifying Transferability Across Biochemical Downstream Tasks.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202301223
Abstract: Proteins are the building blocks of life, carrying out fundamental functions in biology. In computational biology, an effective protein representation facilitates many important biological quantifications. Most existing protein representation methods are derived from self-supervised language… read more here.
Keywords: downstream tasks; representation; biology; protein representation ... See more keywords
A novel methodology on distributed representations of proteins using their interacting ligands
Sign Up to like & getrecommendations! Published in 2018 at "Bioinformatics"
DOI: 10.1093/bioinformatics/bty287
Abstract: Motivation The effective representation of proteins is a crucial task that directly affects the performance of many bioinformatics problems. Related proteins usually bind to similar ligands. Chemical characteristics of ligands are known to capture the… read more here.
Keywords: ligands novel; ligand based; methodology; protein representation ... See more keywords