Safety of Low-Protein Diets and Ketoanalogue Supplementation in CKD
Sign Up to like & getrecommendations! Published in 2018 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2018.02.004
Abstract: D ietary protein restriction, with or without supplementation of ketoanalogues of certain amino acids, have long been considered as an attractive intervention to slow progression of chronic kidney disease (CKD). As suggested by several meta-analyses,… read more here.
Keywords: protein; supplementation; low protein; protein restriction ... See more keywords
Gestational protein restriction alters the RANKL/OPG system in the dental germ of offsprings.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of oral biology and craniofacial research"
DOI: 10.1016/j.jobcr.2020.10.007
Abstract: Evaluate the dentinogenesis in the offspring of rats submitted to gestational protein restriction (GPR). DESIGN The offspring were evaluated at the 21st day of gestation (21 dG). Assessments were made of morphological parameters and the RANKL/OPG… read more here.
Keywords: protein restriction; opg system; rankl opg; gestational protein ... See more keywords
Protein restriction during the fetal period upregulates IL1B and IL13 while suppressing Muc2 expression in the jejunum of mice after weaning.
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition"
DOI: 10.1016/j.nut.2022.111605
Abstract: OBJECTIVE Several recent studies have suggested that malnutrition during developmental periods affects organ function, including that of the small intestine, after birth. However, it is unclear whether carbohydrate or protein restriction during pregnancy affects the… read more here.
Keywords: expression; old mice; protein restriction; mice ... See more keywords
Zone-specific damage of the olfactory epithelium under protein restriction
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-79249-3
Abstract: Oxidative stress causes tissue damage, affecting age-related pathologies. Protein restriction (PR) provides a powerful intervention strategy for reducing oxidative stress, which may have a positive effect on individual organs. However, it is unknown whether PR… read more here.
Keywords: zone; protein restriction; damage; olfactory epithelium ... See more keywords
Gestational protein restriction alters early amygdala neurochemistry in male offspring.
Sign Up to like & getrecommendations! Published in 2022 at "Nutritional neuroscience"
DOI: 10.1080/1028415x.2022.2131064
Abstract: BACKGROUND Gestational protein intake restriction-induced long-lasting harmful outcomes in the offspring's organs and systems. However, few studies have focused on this event's impact on the brain's structures and neurochemical compounds. AIM The present study investigated… read more here.
Keywords: amygdala neurochemical; gestational protein; protein; protein restriction ... See more keywords
Impact of maternal protein restriction on Hypoxia-Inducible Factor (HIF) expression in male fetal kidney development
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1101/2022.03.18.484938
Abstract: Background The kidney ontogenesis is the most structurally affected by gestational protein restriction, reducing close to 30% of their functional units. The reduced nephron number is predictive of hypertension and cardiovascular dysfunctions generally observed in… read more here.
Keywords: kidney; male fetal; hif; protein restriction ... See more keywords
Protein restriction and branched‐chain amino acid restriction promote geroprotective shifts in metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Aging Cell"
DOI: 10.1111/acel.13626
Abstract: The proportion of humans suffering from age‐related diseases is increasing around the world, and creative solutions are needed to promote healthy longevity. Recent work has clearly shown that a calorie is not just a calorie—and… read more here.
Keywords: metabolism; restriction; branched chain; protein restriction ... See more keywords
Neuromuscular junctions (NMJs): ultrastructural analysis and nicotinic acetylcholine receptor (nAChR) subunit mRNA expression in offspring subjected to protein restriction throughout pregnancy
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Experimental Pathology"
DOI: 10.1111/iep.12229
Abstract: Protein restriction during gestation can alter the skeletal muscle phenotype of offspring; however, little is known with regard to whether this also affects the neuromuscular junction (NMJ), as muscle phenotype maintenance depends upon NMJ functional… read more here.
Keywords: protein; nicotinic acetylcholine; protein restriction; expression ... See more keywords
Changes in cardiovascular responses to chemoreflex activation of rats recovered from protein restriction are not related to AT1 receptors
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Physiology"
DOI: 10.1113/ep085791
Abstract: What is the central question of this study? In this study, we sought to investigate whether cardiovascular responses to peripheral chemoreflex activation of rats recovered from protein restriction are related to activation of AT1 receptors.… read more here.
Keywords: rats recovered; recovered protein; protein restriction; activation ... See more keywords
Abstract 4240: Tumor PD-L1 induction associated with dietary protein restriction is modulated by PERK activation
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4240
Abstract: Tumor cells rely on the Integrated Stress Response (ISR) to adapt to different environmental and physiological stresses. The ISR is comprised of four eIF2 kinases that sense different stresses and catalyze phosphorylation of the alpha… read more here.
Keywords: protein; protein restriction; tumor; induction ... See more keywords
Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms.
Sign Up to like & getrecommendations! Published in 2018 at "JCI insight"
DOI: 10.1172/jci.insight.99470
Abstract: Hypertriglyceridemia is an independent risk factor for cardiovascular disease. Dietary interventions based on protein restriction (PR) reduce circulating triglycerides (TGs), but underlying mechanisms and clinical relevance remain unclear. Here, we show that 1 week of… read more here.
Keywords: protein restriction; crebh apoa5; apoa5 expression; crebh ... See more keywords