Profiling of extracellular vesicles of metastatic urothelial cancer patients to discover protein signatures related to treatment outcome
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13288
Abstract: The prognosis of metastatic urothelial carcinoma (mUC) patients is poor, and early prediction of systemic therapy response would be valuable to improve outcome. In this exploratory study, we investigated protein profiles in sequential plasma‐isolated extracellular… read more here.
Keywords: oncology; extracellular vesicles; metastatic urothelial; protein signatures ... See more keywords
Serum protein signatures differentiate paediatric autoimmune/inflammatory disorders.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108790
Abstract: Because of their rarity, limited awareness among non-specialists, and significant overlaps in their clinical presentation, childhood autoimmune/inflammatory conditions represent a diagnostic and therapeutic challenge. Juvenile idiopathic arthritis (JIA), with its 7 sub-forms, is the most… read more here.
Keywords: disease; serum protein; differentiate paediatric; protein signatures ... See more keywords
Urinary exosomes reveal protein signatures in hypertensive patients with albuminuria
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17787
Abstract: Albuminuria is an indicator of cardiovascular risk and renal damage in hypertensive individuals. Chronic renin–angiotensin system (RAS) suppression facilitates blood pressure control and prevents development of new-onset-albuminuria. A significant number of patients, however, develop albuminuria… read more here.
Keywords: exosomes reveal; reveal protein; protein signatures; urinary exosomes ... See more keywords
Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes"
DOI: 10.2337/db19-1070
Abstract: The increasing prevalence of type 2 diabetes poses a major challenge to societies worldwide. Blood-based factors like serum proteins are in contact with every organ in the body to mediate global homeostasis and may thus… read more here.
Keywords: diabetes circulating; type diabetes; protein signatures; signatures causal ... See more keywords
Immunosuppressive Protein Signatures Carried by Syncytiotrophoblast-Derived Exosomes and Their Role in Human Pregnancy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.717884
Abstract: The syncytiotrophoblast (STB) of human placenta constitutively and throughout pregnancy produces and secretes exosomes - nanometer-sized membrane-bound extracellular vesicles from the endosomal compartment that convey cell-cell contact ‘by proxy’ transporting information between donor and recipient… read more here.
Keywords: pregnancy; derived exosomes; protein signatures; signatures carried ... See more keywords