Peroxisomes: new insights into protein sorting, dynamics, quality control, signalling and roles in health and disease
Sign Up to like & getrecommendations! Published in 2019 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-019-01780-w
Abstract: The 6th Open European peroxisome meeting (OEPM) was held on the 26th and 27th of October (2018) in Groningen, the Netherlands. OEPM is a biannual meeting organized by a European peroxisome research group. Previous meetings… read more here.
Keywords: peroxisomes new; sorting dynamics; protein sorting; new insights ... See more keywords
Protein sorting: A new quality control pathway for GPI-anchored proteins
Sign Up to like & getrecommendations! Published in 2021 at "Current Biology"
DOI: 10.1016/j.cub.2021.08.039
Abstract: Glycosylphosphatidylinositol-anchored proteins are a class of lipid-anchored membrane proteins found at the surface of all eukaryotic cells. New work provides genome-wide insights into mechanisms that mediate quality control of the folding of this important protein family. read more here.
Keywords: anchored proteins; quality control; protein sorting; sorting new ... See more keywords
UBL3 modification influences protein sorting to small extracellular vesicles
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06197-y
Abstract: Exosomes, a type of small extracellular vesicles (sEVs), derived from multivesicular bodies (MVBs), mediate cell-to-cell communication by transporting proteins, mRNAs, and miRNAs. However, the molecular mechanism by which proteins are sorted to sEVs is not… read more here.
Keywords: extracellular vesicles; cell; ubl3 modification; modification ... See more keywords
Vacuolar protein sorting 4 is required for silkworm metamorphosis
Sign Up to like & getrecommendations! Published in 2019 at "Insect Molecular Biology"
DOI: 10.1111/imb.12586
Abstract: Vacuolar protein sorting 4 (Vps4) not only functions with its positive regulator vacuolar protein sorting 20‐associated 1 (Vta1) in the multivesicular body (MVB) pathway but also participates alone in MVB‐unrelated cellular processes. However, its physiological… read more here.
Keywords: protein; vacuolar protein; protein sorting; silkworm metamorphosis ... See more keywords
Ubc13-Mms2 cooperates with a family of RING E3s in membrane protein sorting.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cell science"
DOI: 10.1242/jcs.244566
Abstract: Polyubiquitin chains linked via lysine (K) 63 play an important role in endocytosis and membrane trafficking. Their primary source is the ubiquitin protein ligase (E3) Rsp5/NEDD4, which acts as a key regulator of membrane protein… read more here.
Keywords: protein sorting; ubc13 mms2; membrane protein; membrane ... See more keywords
The identification of high-performing antibodies for Vacuolar protein sorting-associated protein 35 (hVPS35) for use in Western Blot, immunoprecipitation and immunofluorescence
Sign Up to like & getrecommendations! Published in 2023 at "F1000Research"
DOI: 10.12688/f1000research.133696.1
Abstract: Vacuolar protein sorting-associated protein 35 is a subunit of the retromer complex, a vital constituent of the endosomal protein sorting pathway. The D620N mutation in the VPS35 gene has been reported to be linked to… read more here.
Keywords: protein sorting; western blot; protein; sorting associated ... See more keywords
Navigating the Controversies of Retromer-Mediated Endosomal Protein Sorting
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.658741
Abstract: The retromer complex was first identified more than 20 years ago through studies conducted in the yeast Saccharomyces cerevisiae. Data obtained using many different model systems have revealed that retromer is a key component of… read more here.
Keywords: navigating controversies; retromer mediated; controversies retromer; endosomal protein ... See more keywords
Protein sorting from endosomes to the TGN
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1140605
Abstract: Retrograde transport from endosomes to the trans-Golgi network is essential for recycling of protein and lipid cargoes to counterbalance anterograde membrane traffic. Protein cargo subjected to retrograde traffic include lysosomal acid-hydrolase receptors, SNARE proteins, processing… read more here.
Keywords: sorting endosomes; protein sorting; transport; retrograde transport ... See more keywords
Corrigendum: The Vacuolar Protein Sorting-38 Subunit of the Arabidopsis Phosphatidylinositol-3-Kinase Complex Plays Critical Roles in Autophagy, Endosome Sorting, and Gravitropism
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2020.00261
Abstract: [This corrects the article DOI: 10.3389/fpls.2018.00781.]. read more here.
Keywords: corrigendum vacuolar; sorting subunit; arabidopsis phosphatidylinositol; vacuolar protein ... See more keywords
The Prognostic Value and the Oncogenic and Immunological Roles of Vacuolar Protein Sorting Associated Protein 26 A in Pancreatic Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043486
Abstract: The identification of the prognostic markers and therapeutic targets might benefit the diagnosis and treatment of pancreatic adenocarcinoma (PAAD), one of the most aggressive malignancies. Vacuolar protein sorting associated protein 26 A (VPS26A) is a… read more here.
Keywords: paad; expression; protein sorting; pancreatic adenocarcinoma ... See more keywords