Ric-8A-mediated stabilization of the trimeric G protein subunit Gαi is inhibited by pertussis toxin-catalyzed ADP-ribosylation.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.036
Abstract: The heterotrimeric G protein subunit Gαi can be activated by G protein-coupled receptors and the cytosolic protein Ric-8A, the latter of which is also known to prevent ubiquitin-dependent degradation of Gαi. Here we show that… read more here.
Keywords: protein; adp ribosylation; adp ribosylated; protein subunit ... See more keywords
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses
Sign Up to like & getrecommendations! Published in 2021 at "Immunity"
DOI: 10.1016/j.immuni.2021.11.001
Abstract: Adjuvants are critical for improving the quality and magnitude of adaptive immune responses to vaccination. Lipid nanoparticle (LNP)-encapsulated nucleoside-modified mRNA vaccines have shown great efficacy against SARS-CoV-2, but the mechanism of action of this vaccine… read more here.
Keywords: mrna protein; protein subunit; helper cell; follicular helper ... See more keywords
Key Roles of TRPV Channels Hg-osm-9, Hg-ocr-2, and G-Protein α Subunit Hg-goa-1 in the Chemosensory Behavior and Parasitism of Heterodera Glycines.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c07304
Abstract: The soybean cyst nematode (SCN, Heterodera glycines) relies on chemosensation for host localization and successful infection. Understanding the molecular basis of chemosensation is critical, as it determines the nematode's ability to locate and invade host… read more here.
Keywords: ocr protein; heterodera glycines; trpv channels; channels osm ... See more keywords
Immunogenicity and protective efficacy of a recombinant protein subunit vaccine and an inactivated vaccine against SARS-CoV-2 variants in non-human primates
Sign Up to like & getrecommendations! Published in 2022 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-022-00926-y
Abstract: Emerging SARS-CoV-2 variants and the gradually decreasing neutralizing antibodies over time post vaccination have led to an increase in incidents of breakthrough infection across the world. To investigate the potential protective effect of the recombinant… read more here.
Keywords: sars cov; variant; protein subunit; recombinant protein ... See more keywords
Sensitive Sequencing Analysis Suggests Thyrotropin Receptor and Guanine Nucleotide-Binding Protein G Subunit Alpha as Sole Driver Mutations in Hot Thyroid Nodules
Sign Up to like & getrecommendations! Published in 2020 at "Thyroid"
DOI: 10.1089/thy.2019.0648
Abstract: Background: Constitutively activating mutations in the thyrotropin receptor (TSHR) and the guanine nucleotide-binding protein G subunit alpha (GNAS) are the primary cause of hot thyroid nodules (HT... read more here.
Keywords: protein subunit; binding protein; thyrotropin receptor; nucleotide binding ... See more keywords
G protein subunit gamma 5 promotes the proliferation, metastasis and glycolysis of breast cancer cells through the Wnt/β-catenin pathway
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001394
Abstract: GNG5 is suggested to exert a critical effect on tumor development in human beings; however, its function and related mechanism within breast cancer (BC) are still unclear. In this regard, the present work focused on… read more here.
Keywords: gng5; protein subunit; wnt catenin; breast cancer ... See more keywords
Recombinant protein subunit COVID‐19 vaccine‐induced Guillain‐Barré Syndrome in an adolescent: A case report
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15466
Abstract: Guillain‐Barré Syndrome (GBS), an autoimmune neurological disease of peripheral nerves, has been causally associated with COVID‐19 vaccination in adults. However, no such report has been published so far in children. We describe a 13‐year‐old female… read more here.
Keywords: protein subunit; covid vaccine; vaccine; subunit covid ... See more keywords
Evaluating passive immunity in piglets from sows vaccinated with a PEDV S protein subunit vaccine
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2024.1498610
Abstract: Porcine epidemic diarrhea virus (PEDV) is a highly contagious virus that causes severe diarrhea and high mortality in neonatal piglets. Current control measures, such as inactivated and live-attenuated vaccines, have limitations in providing complete protection.… read more here.
Keywords: vaccine; subunit vaccine; piglets sows; pedv protein ... See more keywords
Metformin Suppresses Monocyte Immunometabolic Activation by SARS-CoV-2 Spike Protein Subunit 1
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.733921
Abstract: A hallmark of COVID-19 is a hyperinflammatory state associated with severity. Monocytes undergo metabolic reprogramming and produce inflammatory cytokines when stimulated with SARS-CoV-2. We hypothesized that binding by the viral spike protein mediates this effect,… read more here.
Keywords: sars cov; spike protein; protein subunit; cov spike ... See more keywords
Advances in protein subunit vaccines against H1N1/09 influenza
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1499754
Abstract: The A/H1N1pdm09 influenza virus, which caused the 2009 pandemic, has since become a recurring strain in seasonal influenza outbreaks. Given the ongoing threat of influenza, protein subunit vaccines have garnered significant attention for their safety… read more here.
Keywords: h1n1 influenza; subunit vaccines; protein subunit; vaccines h1n1 ... See more keywords
A Comprehensive Review of the Protein Subunit Vaccines Against COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.927306
Abstract: Two years after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), in December 2019, the first infections were identified in Wuhan city of China. SARS-CoV-2 infection caused a global pandemic and accordingly, 5.41 million deaths worldwide. Hence,… read more here.
Keywords: subunit vaccines; protein subunit; vaccine; review protein ... See more keywords