Articles with "protein synthesis" as a keyword



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SGK1 is a signalling hub that controls protein synthesis and proliferation in endothelial cells

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Published in 2020 at "FEBS Letters"

DOI: 10.1002/1873-3468.13901

Abstract: BMP9 is a cytokine involved in the maturation phase of the angiogenic process that signals through its serine/threonine receptor ALK1 and its coreceptor endoglin. In this paper, we explain how BMP9 directs the regulation of… read more here.

Keywords: proliferation; hub controls; protein synthesis; signalling hub ... See more keywords
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Cell‐Free Protein Synthesis: A Cell‐Free Platform Based on Nisin Biosynthesis for Discovering Novel Lanthipeptides and Guiding their Overproduction In Vivo (Adv. Sci. 17/2020)

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Published in 2020 at "Advanced Science"

DOI: 10.1002/advs.202070096

Abstract: In article number 2001616, Tiangang Liu and co-workers develop a cell-free protein synthesis (CFPS) platform that enables rapid discovery of novel lanthipeptides and guides lanthipeptide overproduction in vivo. This study extends the use of cell-free… read more here.

Keywords: cell free; protein synthesis; novel lanthipeptides; cell ... See more keywords
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Development of an E. coli strain for cell-free ADC manufacturing.

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Published in 2021 at "Biotechnology and bioengineering"

DOI: 10.1002/bit.27961

Abstract: Recent advances in cell-free protein synthesis have enabled the folding and assembly of full-length antibodies at high titers with extracts from prokaryotic cells. Coupled with the facile engineering of the E. coli translation machinery, E.… read more here.

Keywords: extract; protein synthesis; cell free;
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Repressor‐Like On‐Off Regulation of Protein Expression by the DNA‐Binding Transcription Activator‐Like Effector in T7 Promoter‐Based Cell‐Free Protein Synthesis

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Published in 2020 at "ChemBioChem"

DOI: 10.1002/cbic.202000591

Abstract: The aim of this study was to develop a transcription activator‐like effector (TALE)‐based technology to regulate protein synthesis in cell‐free systems. We attempted to regulate the T7 promoter system, which has no natural mechanism of… read more here.

Keywords: protein; tale; expression; protein synthesis ... See more keywords
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Cell‐Free Protein Synthesis for the Screening of Novel Azoreductases and Their Preferred Electron Donor

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Published in 2022 at "Chembiochem"

DOI: 10.1002/cbic.202200121

Abstract: Azoreductases are potent biocatalysts for the cleavage of azo bonds. Various gene sequences coding for potential azoreductases are available in databases, but many of their gene products are still uncharacterized. To avoid the laborious heterologous… read more here.

Keywords: preferred electron; electron donor; cell free; free protein ... See more keywords
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Acute rimonabant treatment promotes protein synthesis in C2C12 myotubes through a CB1‐independent mechanism

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Published in 2020 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.30034

Abstract: Sarcopenia is an age‐related loss of muscle mass associated with changes in skeletal muscle protein homeostasis due to lipid accumulation and anabolic resistance; changes that are also commonly described in obesity. Activation of the endocannabinoid… read more here.

Keywords: muscle; effect; protein synthesis; rimonabant ... See more keywords
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Declines in muscle protein synthesis account for short‐term muscle disuse atrophy in humans in the absence of increased muscle protein breakdown

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Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"

DOI: 10.1002/jcsm.13005

Abstract: We determined the short‐term (i.e. 4 days) impacts of disuse atrophy in relation to muscle protein turnover [acute fasted‐fed muscle protein synthesis (MPS)/muscle protein breakdown (MPB) and integrated MPS/estimated MPB]. read more here.

Keywords: muscle protein; disuse atrophy; muscle; protein synthesis ... See more keywords
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Identifying New Small Proteins in Escherichia coli

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Published in 2018 at "Proteomics"

DOI: 10.1002/pmic.201700064

Abstract: The number of small proteins (SPs) encoded in the Escherichia coli genome is unknown, as current bioinformatics and biochemical techniques make short gene and small protein identification challenging. One method of small protein identification involves… read more here.

Keywords: escherichia coli; small proteins; protein synthesis; identifying new ... See more keywords
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Sequestration of eIF4A by angiomotin: A novel mechanism to restrict global protein synthesis in trophoblast cells

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Published in 2020 at "STEM CELLS"

DOI: 10.1002/stem.3305

Abstract: Enrichment of angiomotin (AMOT) in the ectoplacental cone of E7.5 murine placenta prompted our investigation on the role of AMOT in trophoblast differentiation. We show here that AMOT levels increased in mouse placenta during gestation… read more here.

Keywords: eif4a; trophoblast; protein synthesis; amot ... See more keywords
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The Central Dogma revisited: Insights from protein synthesis, CRISPR, and beyond

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Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"

DOI: 10.1002/wrna.1718

Abstract: Francis Crick advanced two distinct but interrelated fundamental principles of molecular biology: (1) the Sequence Hypothesis and (2) the Central Dogma. The Sequence Hypothesis defines biological information transfer as the residue‐by‐residue transfer of sequence information… read more here.

Keywords: information; transfer; dogma; protein synthesis ... See more keywords
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Cell-Free Protein Synthesis of Small Intrinsically Disordered Proteins for NMR Spectroscopy.

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Published in 2020 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-0524-0_11

Abstract: Cell-free protein synthesis (CFPS) is an established method to produce recombinant proteins and has been used in a wide variety of applications. The use of CFPS has almost from the onset been favorably linked to… read more here.

Keywords: nmr spectroscopy; cell free; proteins nmr; protein synthesis ... See more keywords