Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc04813b
Abstract: Bromodomain and extraterminal (BET) proteins, a family of epigenetic regulators, have emerged as important oncology drug targets. BET proteins have not been targeted for molecular imaging of cancer. Here, we report the development of a… read more here.
Keywords: targeted probe; bromodomain extraterminal; enables tumour; probe enables ... See more keywords
Programmed Cell Death Protein‐1 (PD‐1)‐Targeted Immunotherapy for Advanced Hepatocellular Carcinoma in Real World
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DOI: 10.2147/ott.s234868
Abstract: Background Hepatocellular carcinoma (HCC) is one of the most common malignant solid tumors. Its incidence is increasing worldwide due to the dissemination of hepatitis B infection, HCV infection and nonalcoholic steatohepatitis-related HCC. For patients with… read more here.
Keywords: cell death; hepatocellular carcinoma; death protein; carcinoma ... See more keywords
Protein-Targeted Degradation Agents Based on Natural Products
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DOI: 10.3390/ph16010046
Abstract: Natural products are an important source of drug lead compounds, and natural products with significant biological activity are constantly being discovered and used in clinical practice. At present, natural products play an important role in… read more here.
Keywords: natural products; targeted degradation; degradation agents; protacs molecular ... See more keywords