D‐Peptide and D‐Protein Technology: Recent Advances, Challenges, and Opportunities **
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DOI: 10.1002/cbic.202200537
Abstract: Total chemical protein synthesis provides access to entire D‐protein enantiomers enabling unique applications in molecular biology, structural biology, and bioactive compound discovery. Key enzymes involved in the central dogma of molecular biology have been prepared… read more here.
Keywords: challenges opportunities; peptide protein; technology recent; protein technology ... See more keywords
Caspase-Based Fusion Protein Technology: Substrate Cleavability Described by Computational Modeling and Simulation
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Chemical Information and Modeling"
DOI: 10.1021/acs.jcim.4c00316
Abstract: The Caspase-based fusion protein technology (CASPON) allows for universal cleavage of fusion tags from proteins of interest to reconstitute the native N-terminus. While the CASPON enzyme has been optimized to be promiscuous against a diversity… read more here.
Keywords: fusion protein; fusion; caspase based; protein technology ... See more keywords