Comprehensive Analysis of Protein N-terminome by Guanidination of Terminal Amines.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b04141
Abstract: Protein N-termini and their modifications not only represent different protein isoforms, but also relate to the functional annotation and proteolytic activities. Currently, negative selection methods, such as terminal amine isotopic labeling of substrates (TAILS), are… read more here.
Keywords: protein; protein terminome; free amines; cleavage ... See more keywords
NAPT, an unbiased approach for sequential analysis of the protein N- and C-terminome.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc03778e
Abstract: Protein termini are generally associated with protein stability. Taking advantage of charge state differences between terminal peptides and internal peptides, we developed a new method termed LysargiNase-assisted Analysis of the Protein N- and C-Terminome (NAPT)… read more here.
Keywords: terminome napt; protein terminome; analysis protein; protein termini ... See more keywords