Endomembrane Protein Trafficking Regulated by a TvCyP2 Cyclophilin in the Protozoan Parasite, Trichomonas vaginalis
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-58270-6
Abstract: In Trichomonas vaginalis, the TvCyP1-catalyzed conformational switches of two glycinyl-prolyl imide bonds in Myb3 were previously shown to regulate the trafficking of Myb3 from cytoplasmic membrane compartments towards the nucleus. In this study, TvCyP2 was… read more here.
Keywords: protein trafficking; microscopy; tvcyp1 tvcyp2; tvcyp2 ... See more keywords
Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e18-10-0678
Abstract: The dynein-2 complex drives retrograde ciliary protein trafficking by associating with the intraflagellar transport (IFT) machinery, containing IFT-A and IFT-B complexes. We recently showed that the dynein-2 complex, which comprises 11 subunits, can be divided… read more here.
Keywords: chain; light; protein trafficking; intermediate chain ... See more keywords
The Trafficking Machinery of Lytic and Protein Storage Vacuoles: How Much is Shared and How Much is Distinct?
Sign Up to like & getrecommendations! Published in 2021 at "Journal of experimental botany"
DOI: 10.1093/jxb/erab067
Abstract: Plant cells contain two types of vacuoles, the lytic vacuole and the protein storage vacuole. Lytic vacuoles (LVs) are present in vegetative cells, whereas protein storage vacuoles (PSVs) are found in seed cells. The physiological… read more here.
Keywords: protein; protein trafficking; storage vacuoles; protein storage ... See more keywords
Methodological caveats regarding “Novel insights into surfactant protein C trafficking revealed through the study of a pathogenic mutant”
Sign Up to like & getrecommendations! Published in 2022 at "European Respiratory Journal"
DOI: 10.1183/13993003.02974-2021
Abstract: We read with great interest the paper by Dickens et al. [1] entitled “Novel insights into surfactant protein C trafficking revealed through the study of a pathogenic mutant” recently published in the European Respiratory Journal.… read more here.
Keywords: protein trafficking; novel insights; insights surfactant; surfactant protein ... See more keywords
Protein Trafficking or Cell Signaling: A Dilemma for the Adaptor Protein TOM1
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.643769
Abstract: Lysosomal degradation of ubiquitinated transmembrane protein receptors (cargo) relies on the function of Endosomal Sorting Complex Required for Transport (ESCRT) protein complexes. The ESCRT machinery is comprised of five unique oligomeric complexes with distinct functions.… read more here.
Keywords: protein; tom1; protein trafficking; cargo sorting ... See more keywords
Phosphorylation and Ubiquitylation Regulate Protein Trafficking, Signaling, and the Biogenesis of Primary Cilia
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DOI: 10.3389/fcell.2021.664279
Abstract: The primary cilium is a solitary, microtubule-based membrane protrusion extending from the surface of quiescent cells that senses the cellular environment and triggers specific cellular responses. The functions of primary cilia require not only numerous… read more here.
Keywords: protein trafficking; phosphorylation ubiquitylation; biogenesis; primary cilia ... See more keywords
TORC1 Signaling Controls the Stability and Function of α-Arrestins Aly1 and Aly2
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DOI: 10.3390/biom12040533
Abstract: Nutrient supply dictates cell signaling changes, which in turn regulate membrane protein trafficking. To better exploit nutrients, cells relocalize membrane transporters via selective protein trafficking. Key in this reshuffling are the α-arrestins, selective protein trafficking… read more here.
Keywords: protein trafficking; torc1 signaling; aly1 aly2; arrestins aly1 ... See more keywords