Targeting ER protein TXNDC5 in hepatic stellate cell mitigates liver fibrosis by repressing non-canonical TGFβ signalling
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DOI: 10.1136/gutjnl-2021-325065
Abstract: Background and objectives Liver fibrosis (LF) occurs following chronic liver injuries. Currently, there is no effective therapy for LF. Recently, we identified thioredoxin domain containing 5 (TXNDC5), an ER protein disulfide isomerase (PDI), as a… read more here.
Keywords: protein txndc5; liver fibrosis; txndc5; fibrosis ... See more keywords