Eudragit® L100-coated mannosylated chitosan nanoparticles for oral protein vaccine delivery.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.02.016
Abstract: The aim of this study was to develop a novel biodegradable polymeric carrier for the delivery of protein vaccine orally in order to target the antigen presenting cells (APCs) in the region of Peyer's patches… read more here.
Keywords: protein vaccine; delivery; eudragit l100; mcs nps ... See more keywords
Recombinant Erns-E2 protein vaccine formulated with MF59 and CPG-ODN promotes T cell immunity against bovine viral diarrhea virus infection.
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2020.03.020
Abstract: To obtain an effective vaccine candidate against bovine viral diarrhea virus (BVDV) disease which causes great economical loss in cattle industries, recombinant Erns-E2 protein vaccine containing MF59 and CPG-ODN adjuvants was prepared and assessed in… read more here.
Keywords: protein vaccine; cpg odn; recombinant erns; erns protein ... See more keywords
Development and evaluation of a new recombinant protein vaccine (YidR) against Klebsiella pneumoniae infection.
Sign Up to like & getrecommendations! Published in 2020 at "Vaccine"
DOI: 10.1016/j.vaccine.2020.03.057
Abstract: Vaccination is a promising approach to prevent Klebsiella infection; however, the high heterogeneity of strains is a limiting factor. The best antigenic target for an anti-Klebsiella vaccine should be expressed by all or most of… read more here.
Keywords: protein vaccine; klebsiella; yidr; immunized mice ... See more keywords
Preclinical evaluation of bacterially produced RSV-G protein vaccine: Strong protection against RSV challenge in cotton rat model
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42428
Abstract: In current study, we evaluated the safety and protective efficacy of recombinant unglycosylated RSV G protein ectodomain produced in E. coli (in presence and absence of oil-in-water adjuvant) in a preclinical RSV susceptible cotton rat… read more here.
Keywords: protein; protein vaccine; rsv protein; cotton rat ... See more keywords
A Novel PspA Protein Vaccine Intranasal Delivered by Bacterium-Like Particles Provides Broad Protection Against Pneumococcal Pneumonia in Mice
Sign Up to like & getrecommendations! Published in 2018 at "Immunological Investigations"
DOI: 10.1080/08820139.2018.1439505
Abstract: ABSTRACT Background: Streptococcus pneumoniae is a major pathogen accounting for a large number of pneumococcal disease in worldwide. Due to the mucosal immune pathway induces both systemic and mucosal immune responses, the potential strategy to… read more here.
Keywords: protein; protein vaccine; pspa; mucosal ... See more keywords
Chimeric immune checkpoint protein vaccines inhibit the tumorigenesis and growth of rat cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.982196
Abstract: Cholangiocarcinoma (CCA) is the second most common primary liver malignancy and carries a dismal prognosis due to difficulties in achieving an optimal resection, and poor response to current standard-of-care systemic therapies. We previously devised a… read more here.
Keywords: tumor; rat; protein vaccine; protein vaccines ... See more keywords
A Novel Single-Stranded RNA-Based Adjuvant Improves the Immunogenicity of the SARS-CoV-2 Recombinant Protein Vaccine
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14091854
Abstract: The research and development (R&D) of novel adjuvants is an effective measure for improving the immunogenicity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recombinant protein vaccine. Toward this end, we designed a novel… read more here.
Keywords: rna based; immunogenicity; cov recombinant; protein vaccine ... See more keywords