Functional effects of protein variants.
Sign Up to like & getrecommendations! Published in 2020 at "Biochimie"
DOI: 10.1016/j.biochi.2020.10.009
Abstract: Genetic and other variations frequently affect protein functions. Scientific articles can contain confusing descriptions about which function or property is affected, and in many cases the statements are pure speculation without any experimental evidence. To… read more here.
Keywords: protein variants; framework; specificity affinity; effects protein ... See more keywords
Implications derived from S-protein variants of SARS-CoV-2 from six continents
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Biological Macromolecules"
DOI: 10.1016/j.ijbiomac.2021.09.080
Abstract: Spike (S) protein is a critical determinant of the infectivity and antigenicity of SARS-CoV-2. Several mutations in the spike protein of SARS-CoV-2 have already been detected, and their effect in immune system evasion and enhanced… read more here.
Keywords: protein variants; derived protein; implications derived; sars cov ... See more keywords
Positive selection and precipitation effects on the mitochondrial NADH dehydrogenase subunit 6 gene in brown hares (Lepus europaeus) under a phylogeographic perspective
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DOI: 10.1371/journal.pone.0224902
Abstract: Previous studies in hares and jackrabbits have indicated that positive selection has shaped the genetic diversity of mitochondrial genes involved in oxidative phosphorylation, which may affect cellular energy production and cause regional adaptation to different… read more here.
Keywords: protein variants; positive selection; brown hares; nadh dehydrogenase ... See more keywords
Capture Sequencing to Explore and Map Rare Casein Variants in Goats
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.620253
Abstract: Genetic variations in the four casein genes CSN1S1, CSN2, CSN1S2, and CSN3 have obtained substantial attention since they affect the milk protein yield, milk composition, cheese processing properties, and digestibility as well as tolerance in… read more here.
Keywords: protein variants; nubian ibex; ibex; casein ... See more keywords
Review: Genetic and protein variants of milk caseins in goats
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.995349
Abstract: The milk casein genes in goats, are highly polymorphic genes with numerous synonymous and non-synonymous mutations. So far, 20 protein variants have been reported in goats for alpha-S1-casein, eight for beta-casein, 14 for alpha-S2-casein, and… read more here.
Keywords: casein; review genetic; casein genes; milk ... See more keywords
Enhancing the Immunogenicity of RBD Protein Variants through Amino Acid E484 Mutation in SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14092020
Abstract: In the context of the COVID-19 pandemic, conducting antibody testing and vaccination is critical. In particular, the continued evolution of SARS-CoV-2 raises concerns about the effectiveness of vaccines currently in use and the activity of… read more here.
Keywords: rbd protein; immunogenicity; protein variants; sars cov ... See more keywords
An issue of concern: unique truncated ORF8 protein variants of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2022 at "PeerJ"
DOI: 10.7717/peerj.13136
Abstract: Open reading frame 8 (ORF8) shows one of the highest levels of variability among accessory proteins in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus Disease 2019 (COVID-19). It was previously… read more here.
Keywords: unique truncated; sars cov; truncated orf8; orf8 protein ... See more keywords