Protein-water hydrogen-bond networks of G Protein-Coupled Receptors: graph-based analyses of static structures and molecular dynamics.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2020.107634
Abstract: Protein and protein-water hydrogen bonds are thought to shape the conformational energy landscape of G Protein-Coupled Receptors, GPCRs. As numerous static structures of GPCRs have been solved, the important question arises whether GPCR structures and… read more here.
Keywords: bond networks; bond; hydrogen bond; protein water ... See more keywords
Fast-microsecond dynamics of the protein-water network in the active site of human carbonic anhydrase II by solid-state NMR spectroscopy.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b05311
Abstract: Protein-water interactions have widespread effects on protein structure and dynamics. As such, the function of many bio-macromolecules can be directly related to the presence and exchange of water molecules. While the presence of structural water… read more here.
Keywords: solid state; network; water; pocket ... See more keywords
Quantum mechanics of proteins in explicit water: The role of plasmon-like solute-solvent interactions
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aax0024
Abstract: Plasmon-like interactions stabilize folded protein states and offer a long-range interaction mechanism for solvated biomolecules. Quantum-mechanical van der Waals dispersion interactions play an essential role in intraprotein and protein-water interactions—the two main factors affecting the… read more here.
Keywords: water; plasmon like; role; protein water ... See more keywords
Graphs of protein-water hydrogen bond networks to dissect structural movies of ion-transfer microbial rhodopsins
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.1075648
Abstract: Microbial rhodopsins are membrane proteins that use the energy absorbed by the covalently bound retinal chromophore to initiate reaction cycles resulting in ion transport or signal transduction. Thousands of distinct microbial rhodopsins are known and,… read more here.
Keywords: graphs protein; structural movies; protein water; microbial rhodopsins ... See more keywords
Egg Yolk Protein Water Extracts Modulate the Immune Response in BALB/c Mice with Immune Dysfunction Caused by Forced Swimming
Sign Up to like & getrecommendations! Published in 2022 at "Foods"
DOI: 10.3390/foods11010121
Abstract: The objective of this study was to determine the immunomodulatory effects of egg yolk protein–water extract (EYW) on splenocyte proliferation, cytokine secretion, immunoglobulin production, and NK cell cytotoxic activity in BALB/c mice. The forced swimming… read more here.
Keywords: balb mice; eyw supplementation; supplementation; protein water ... See more keywords