Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.10.161
Abstract: Myelin protein zero-like protein 1 (MPZL1) is a member of the immunoglobulin superfamily, and is also a receptor of concanavalin A (ConA). MPZL1 is upregulated in hepatocellular carcinoma (HCC) and accelerates migration of HCC cells.… read more here.
Keywords: protein; zero like; like protein; extracellular domain ... See more keywords
A nonsense mutation in myelin protein zero causes congenital hypomyelination neuropathy through altered P0 membrane targeting and gain of abnormal function
Sign Up to like & getrecommendations! Published in 2019 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddy336
Abstract: Abstract Protein zero (P0) is the major structural protein in peripheral myelin, and mutations in the Myelin Protein Zero (Mpz) gene produce wide‐ranging hereditary neuropathy phenotypes. To gain insight in the mechanisms underlying a particularly… read more here.
Keywords: protein; abnormal function; hypomyelination; gain abnormal ... See more keywords