Serine proteinases in the turnover of the cartilage extracellular matrix in the joint: implications for therapeutics
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DOI: 10.1111/bph.14173
Abstract: Cartilage destruction is a key characteristic of arthritic disease, a process now widely established to be mediated by metzincins such as MMPs. Despite showing promise in preclinical trials during the 1990s, MMP inhibitors for the… read more here.
Keywords: cartilage extracellular; proteinases turnover; turnover cartilage; extracellular matrix ... See more keywords