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Mechanisms of TDP-43 Proteinopathy Onset and Propagation

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0 Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22116004

Abstract: TDP-43 is an RNA-binding protein that has been robustly linked to the pathogenesis of a number of neurodegenerative disorders, including amyotrophic lateral sclerosis and frontotemporal dementia. While mutations in the TARDBP gene that codes for… read more here.

Keywords: pathogenesis; onset propagation; tdp proteinopathy; mechanisms tdp ... See more keywords