ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma
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DOI: 10.1016/j.celrep.2019.08.088
Abstract: Summary The glucocorticoid receptor (GR) acts as a ubiquitous cortisol-dependent transcription factor (TF). To identify co-factors, we used protein-fragment complementation assays and found that GR recognizes FLI1 and additional ETS family proteins, TFs relaying proliferation… read more here.
Keywords: treatment; ets proteins; glucocorticoid receptors; proteins bind ... See more keywords
An improved method for the isolation and identification of unknown proteins that bind to known DNA sequences by affinity capture and mass spectrometry
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DOI: 10.1371/journal.pone.0202602
Abstract: Transcription of a gene can be regulated at many different levels. One such fundamental level is interaction between protein and DNA. Protein(s) binds to distinct sites on the DNA, which activate, enhance or repress transcription.… read more here.
Keywords: dna; method isolation; proteins bind; improved method ... See more keywords