Intrinsically disordered proteins and biomolecular condensates as drug targets.
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DOI: 10.1016/j.cbpa.2021.02.009
Abstract: Intrinsically disordered domains represent attractive therapeutic targets because they play key roles in cancer, as well as in neurodegenerative and infectious diseases. They are, however, considered undruggable because they do not form stable binding pockets… read more here.
Keywords: biomolecular condensates; condensates drug; proteins biomolecular; disordered proteins ... See more keywords