Hedgehog proteins create a dynamic cholesterol interface
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DOI: 10.1371/journal.pone.0246814
Abstract: During formation of the Hedgehog (Hh) signaling proteins, cooperative activities of the Hedgehog INTein (Hint) fold and Sterol Recognition Region (SRR) couple autoproteolysis to cholesterol ligation. The cholesteroylated Hh morphogens play essential roles in embryogenesis,… read more here.
Keywords: proteins create; hedgehog; cholesterol; create dynamic ... See more keywords