Autonomous Synthesis of Functional, Permanently Phosphorylated Proteins for Defining the Interactome of Monomeric 14-3-3ζ
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DOI: 10.1021/acscentsci.3c00191
Abstract: 14-3-3 proteins are dimeric hubs that bind hundreds of phosphorylated “clients” to regulate their function. Installing stable, functional mimics of phosphorylated amino acids into proteins offers a powerful strategy to study 14-3-3 function in cellular-like… read more here.
Keywords: synthesis functional; proteins defining; phosphorylated proteins; permanently phosphorylated ... See more keywords