Fuzzy Drug Targets: Disordered Proteins in the Drug-Discovery Realm
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c07708
Abstract: Intrinsically disordered proteins (IDPs) and regions (IDRs) form a large part of the eukaryotic proteome. Contrary to the structure–function paradigm, the disordered proteins perform a myriad of functions in vivo. Consequently, they are involved in… read more here.
Keywords: proteins drug; disordered proteins; targets disordered; fuzzy drug ... See more keywords
Phages, anti-CRISPR proteins, and drug-resistant bacteria: what do we know about this triad?
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens and disease"
DOI: 10.1093/femspd/ftac039
Abstract: Phages are viruses that infect bacteria, relying on their genetic machinery to replicate. To survive the constant attack of phages, bacteria have developed diverse defense strategies to act against them. Nevertheless, phages rapidly co-evolve to… read more here.
Keywords: proteins drug; crispr proteins; anti crispr; phages anti ... See more keywords
Efficient Data Mining Algorithms for Screening Potential Proteins of Drug Target
Sign Up to like & getrecommendations! Published in 2017 at "Mathematical Problems in Engineering"
DOI: 10.1155/2017/9852063
Abstract: The past few decades have witnessed the boom in pharmacology as well as the dilemma of drug development. Playing a crucial role in drug design, the screening of potential human proteins of drug targets from… read more here.
Keywords: dtps; screening potential; drug; drug target ... See more keywords