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Loss of adipose TET proteins enhances β-adrenergic responses and protects against obesity by epigenetic regulation of β3-AR expression

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2205626119

Abstract: Significance The β3-adrenergic receptor (β3-AR) is a major regulator of energy expenditure that triggers lipolysis and thermogenesis in adipose tissue, thereby significantly attenuating the risk of obesity. Obesity is associated with diminished β3-AR expression and… read more here.

Keywords: adipose tet; loss adipose; expression; tet proteins ... See more keywords