Chronic activation of PPARĪ± with fenofibrate reduces autophagic proteins in the liver of mice independent of FGF21
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DOI: 10.1371/journal.pone.0173676
Abstract: Autophagy is a catabolic mechanism to degrade cellular components to maintain cellular energy levels during starvation, a condition where PPARĪ± may be activated. Here we report a reduced autophagic capacity in the liver following chronic… read more here.
Keywords: ppar; autophagic proteins; chronic activation; ppar fenofibrate ... See more keywords
Structural changes of proteins in liver cirrhosis and consequential changes in their function
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DOI: 10.3748/wjg.v28.i29.3780
Abstract: The liver is the site of synthesis of the majority of circulating proteins. Besides initial polypeptide synthesis, sophisticated machinery is involved in the further processing of proteins by removing parts of them and/or adding functional… read more here.
Keywords: liver cirrhosis; changes proteins; changes function; proteins liver ... See more keywords