Proteins and Metabolites fingerprints of Gestational Diabetes Mellitus forming Protein-Metabolite Interactomes are its potential biomarkers.
Sign Up to like & getrecommendations! Published in 2023 at "Proteomics"
DOI: 10.1002/pmic.202200257
Abstract: Gestational diabetes mellitus (GDM) is a consequence of glucose intolerance with an inadequate production of insulin that happens during pregnancy and leads to adverse health consequences for both mother and fetus. GDM patients are at… read more here.
Keywords: gdm; metabolites fingerprints; protein metabolite; proteins metabolites ... See more keywords
Differential Analysis of Mycelial Proteins and Metabolites From Rigidoporus Microporus During In Vitro Interaction With Hevea Brasiliensis.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial ecology"
DOI: 10.1007/s00248-021-01757-0
Abstract: Rigidoporus microporus is the fungus accountable for the white root rot disease that is detrimental to the rubber tree, Hevea brasiliensis. The pathogenicity mechanism of R. microporus and the identity of the fungal proteins and… read more here.
Keywords: proteins metabolites; hevea brasiliensis; analysis; rigidoporus microporus ... See more keywords
Modification of Proteins by Metabolites in Immunity.
Sign Up to like & getrecommendations! Published in 2020 at "Immunity"
DOI: 10.1016/j.immuni.2020.09.014
Abstract: Immunometabolism has emerged as a key focus for immunologists, with metabolic change in immune cells becoming as important a determinant for specific immune effector responses as discrete signaling pathways. A key output for these changes… read more here.
Keywords: immunity; proteins metabolites; immunity modification; modification proteins ... See more keywords
Metal-Polyphenol Network-Mediated Protein Encapsulation Strategy Facilitating the Separation of Proteins and Metabolites in Biospecimens.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03070
Abstract: Access to both protein and metabolite biomarker information in biospecimens from trace samples remains a significant challenge, and it is necessary to separate proteins and metabolites before analysis. In this work, the Fe3O4@SiO2@Proteins@Metal-polyphenol network (MPN)… read more here.
Keywords: metal polyphenol; polyphenol network; proteins metabolites; protein ... See more keywords
Analysis of the uterine lumen in fertility-classified heifers: II. Proteins and metabolitesâ€
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz197
Abstract: Abstract Survival and growth of the bovine conceptus is dependent on endometrial secretions or histotroph. Previously, serial blastocyst transfer was used to classify heifers as high fertile (HF), subfertile (SF), or infertile (IF). Here, we… read more here.
Keywords: classified heifers; proteins metabolites; ulf pregnant; fertility classified ... See more keywords
Local burn wound environment versus systemic response: Comparison of proteins and metabolites
Sign Up to like & getrecommendations! Published in 2022 at "Wound Repair and Regeneration"
DOI: 10.1111/wrr.13042
Abstract: In this study, paired blood plasma (BP) and blister fluid (BF) samples from five paediatric burn patients were analysed using mass spectrometry to compare their protein and metabolite composition. The relative quantification of proteins was… read more here.
Keywords: wound; wound environment; proteins metabolites; local burn ... See more keywords
Abstract 6606: Biomarker discovery in non-small-cell lung cancer enabled by deep multi-omics profiling of proteins, metabolites, transcripts, and genes in blood
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-6606
Abstract: Lung cancer is the leading cause of cancer-related deaths in the United States, with estimates of 236,740 new cases and 118,830 deaths in 2022 secondary to the disease. Blood-based liquid biopsies hold promise to reduce… read more here.
Keywords: lung cancer; multi omics; proteins metabolites; blood ... See more keywords
MicroRNA, Proteins, and Metabolites as Novel Biomarkers for Prediabetes, Diabetes, and Related Complications
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2018.00180
Abstract: Type 2 diabetes mellitus (T2DM) is no more a lifestyle disease of developed countries. It has emerged as a major health problem worldwide including developing countries. However, how diabetes could be detected at an early… read more here.
Keywords: proteins metabolites; metabolites novel; disease; novel biomarkers ... See more keywords
Integrated Proteomics and Metabolomics Analysis in Pregnant Rat Hippocampus After Circadian Rhythm Inversion
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.941585
Abstract: To investigate the changes in proteins, metabolites, and related mechanisms in the hypothalamus of pregnant rats after circadian rhythm inversion during the whole pregnancy cycle. A total of 12 Wistar female rats aged 7 weeks… read more here.
Keywords: rhythm; analysis; rhythm inversion; proteins metabolites ... See more keywords
Identification of Potential Therapeutic Targets on the Level of DNA/mRNAs, Proteins and Metabolites: A Systematic Mapping Review of Scientific Texts’ Fragments from Open Targets
Sign Up to like & getrecommendations! Published in 2023 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb45040223
Abstract: Database records contain useful information, which is readily available, but, unfortunately, limited compared to the source (publications). Our study reviewed the text fragments supporting the association between the biological macromolecules and diseases from Open Targets… read more here.
Keywords: open targets; identification potential; level dna; proteins metabolites ... See more keywords