Multiple reaction monitoring assays for large-scale quantitation of proteins from 20 mouse organs and tissues
Sign Up to like & getrecommendations! Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-023-05687-0
Abstract: Development of MRM-MS assays for 2118 proteins in 20 mouse tissues enables accurate quantitation. Protein concentrations measured from 3 mouse strains using these assays demonstrate proteomic phenotyping and are provided in an online database. Mouse… read more here.
Keywords: proteins mouse; multiple reaction; quantitation; reaction monitoring ... See more keywords
Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons
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DOI: 10.7554/elife.77987
Abstract: Auxin-inducible degrons are a chemical genetic tool for targeted protein degradation and are widely used to study protein function in cultured mammalian cells. Here, we develop CRISPR-engineered mouse lines that enable rapid and highly specific… read more here.
Keywords: auxin inducible; inducible degrons; proteins mouse; endogenous proteins ... See more keywords