Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.77987
Abstract: Auxin-inducible degrons are a chemical genetic tool for targeted protein degradation and are widely used to study protein function in cultured mammalian cells. Here, we develop CRISPR-engineered mouse lines that enable rapid and highly specific… read more here.
Keywords: auxin inducible; inducible degrons; proteins mouse; endogenous proteins ... See more keywords