Bioconjugates of Chelators with Peptides and Proteins in Nuclear Medicine: Historical Importance, Current Innovations and Future Challenges.
Sign Up to like & getrecommendations! Published in 2020 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.0c00015
Abstract: Molecular radiopharmaceuticals based on bioconjugates of chelators with peptides and proteins have had significant clinical impact in diagnosis and treatment of several types of cancers. In the 1990s, indium-111 and yttrium-90 labelled chelator-peptide/protein conjugates established… read more here.
Keywords: medicine; nuclear medicine; bioconjugates chelators; peptides proteins ... See more keywords
DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex
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DOI: 10.1038/s41467-018-03313-w
Abstract: The nuclear pore complex (NPC) is the gatekeeper for nuclear transport in eukaryotic cells. A key component of the NPC is the central shaft lined with intrinsically disordered proteins (IDPs) known as FG-Nups, which control… read more here.
Keywords: dna origami; pore complex; proteins nuclear; nuclear pore ... See more keywords