PLZF and its fusion proteins are pomalidomide-dependent CRBN neosubstrates
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DOI: 10.1038/s42003-021-02801-y
Abstract: Pomalidomide and lenalidomide are immunomodulatory agents that were derived from thalidomide. Cereblon (CRBN) is a common direct target of thalidomide and related compounds and works as a Cullin Ring 4 E3 ubiquitin ligase (CRL4) with… read more here.
Keywords: crbn; fusion proteins; proteins pomalidomide; pomalidomide dependent ... See more keywords