Lipid Nanoparticle Delivery of Small Proteins for Potent In Vivo RAS Inhibition.
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DOI: 10.1021/acsami.3c01501
Abstract: Mutated RAS proteins are potent oncogenic drivers and have long been considered "undruggable". While RAS-targeting therapies have recently shown promise, there remains a clinical need for RAS inhibitors with more diverse targets. Small proteins represent… read more here.
Keywords: nanoparticle delivery; small proteins; lipid nanoparticle; delivery small ... See more keywords