G-Quadruplex-Binding Proteins: Promising Targets for Drug Design
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DOI: 10.3390/biom12050648
Abstract: G-quadruplexes (G4s) are non-canonical secondary nucleic acid structures. Sequences with the potential to form G4s are abundant in regulatory regions of the genome including telomeres, promoters and 5′ non-coding regions, indicating they fulfill important genome… read more here.
Keywords: quadruplex binding; promising targets; targets drug; binding proteins ... See more keywords
Peripheral Membrane Proteins: Promising Therapeutic Targets across Domains of Life
Sign Up to like & getrecommendations! Published in 2021 at "Membranes"
DOI: 10.3390/membranes11050346
Abstract: Membrane proteins can be classified into two main categories—integral and peripheral membrane proteins—depending on the nature of their membrane interaction. Peripheral membrane proteins are highly unique amphipathic proteins that interact with the membrane indirectly, using… read more here.
Keywords: membrane proteins; therapeutic targets; proteins promising; promising therapeutic ... See more keywords