Neuronal proteins as targets of 3-hydroxykynurenine: Implications in neurodegenerative diseases.
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DOI: 10.1021/acschemneuro.9b00265
Abstract: The neurotoxic activity of the tryptophan metabolite 3-hydroxykynurenine (3OHKyn) in neurodegenerative disorders as Parkinson's and Alzheimer's diseases, is related to oxidative stress and 3OHKyn interaction with cellular proteins. The pattern of protein modification induced by… read more here.
Keywords: targets hydroxykynurenine; hydroxykynurenine implications; neurodegenerative diseases; implications neurodegenerative ... See more keywords