Single-nephron proteomes connect morphology and function in proteinuric kidney disease.
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DOI: 10.1016/j.kint.2017.12.012
Abstract: In diseases of many parenchymatous organs, heterogeneous deterioration of individual functional units determines the clinical prognosis. However, the molecular characterization at the level of such individual subunits remains a technological challenge that needs to be… read more here.
Keywords: kidney; single nephron; disease single; proteinuric kidney ... See more keywords
Flot2 acts as a novel mediator of podocyte injury in proteinuric kidney disease
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.78945
Abstract: Podocyte injury is a common hallmark of chronic kidney disease (CKD). The podocin-nephrin complex localized in lipid rafts of podocyte is vital to reduce podocyte injury and proteinuria, however, the mechanism underlying its localization remains… read more here.
Keywords: proteinuric kidney; injury; podocyte injury; kidney disease ... See more keywords