Improving Proteoform Identifications in Complex Systems Through Integration of Bottom-Up and Top-Down Data.
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DOI: 10.1021/acs.jproteome.0c00332
Abstract: Cellular functions are performed by a vast and diverse set of proteoforms. Proteoforms are the specific forms of proteins produced as a result of genetic variations, RNA splicing, and post-translational modifications (PTMs). Top-down mass spectrometric… read more here.
Keywords: bottom top; analysis; proteoform; proteoform identifications ... See more keywords