Proteoform-Specific Protein Binding of Small Molecules in Complex Matrices.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical biology"
DOI: 10.1021/acschembio.6b01018
Abstract: Characterizing the specific binding between protein targets and small molecules is critically important for drug discovery. Conventional assays require isolation and purification of small molecules from complex matrices through multistep chromatographic fractionation, which may alter… read more here.
Keywords: small molecules; proteoform specific; molecules complex; complex matrices ... See more keywords