Proteolysis at work: when time matters for a sensory organelle
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202200137
Abstract: present in metabolism, differentiation, and development. Derangement of ciliary structures and activities underlies the pathogenesis of severe genetic disorders,alsoknownasciliopathies.Theprimaryciliumisformeddur-ing G1 phase of the and disassembled at the G2/M phase transition. Dynamics of the primary cilium… read more here.
Keywords: work time; proteolysis work; matters sensory; proteolysis ... See more keywords
Identification and CRISPR/Cas9 Knockout of the Endogenous C1s Protease in CHO Cells Eliminates Aberrant Proteolysis of Recombinantly Expressed Proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.27016
Abstract: Proteolysis associated with recombinant protein expression in Chinese Hamster Ovary (CHO) cells has hindered the development of biologics including HIV vaccines. When expressed in CHO cells, the recombinant HIV envelope protein, gp120, undergoes proteolytic clipping… read more here.
Keywords: proteolysis; protease; cho cells; c1s protease ... See more keywords
Effects of histatin 5 modifications on antifungal activity and kinetics of proteolysis
Sign Up to like & getrecommendations! Published in 2019 at "Protein Science"
DOI: 10.1002/pro.3767
Abstract: Histatin 5 (Hst‐5) is an antimicrobial peptide with strong antifungal activity against Candida albicans, an opportunistic pathogen that is a common cause of oral thrush. The peptide is natively secreted by human salivary glands and… read more here.
Keywords: single residue; proteolysis; effects histatin; histatin modifications ... See more keywords
A conserved C-terminal peptide of sorghum phosphoenolpyruvate carboxylase promotes its proteolysis, which is prevented by Glc-6P or the phosphorylation state of the enzyme
Sign Up to like & getrecommendations! Published in 2021 at "Planta"
DOI: 10.1007/s00425-021-03692-3
Abstract: Main conclusion A synthetic peptide from the C-terminal end of C4-phosphoenolpyruvate carboxylase is implicated in the proteolysis of the enzyme, and Glc-6P or phosphorylation of the enzyme modulate this effect. Abstract Phosphoenolpyruvate carboxylase (PEPC) is… read more here.
Keywords: glc phosphorylation; proteolysis; phosphoenolpyruvate carboxylase; enzyme ... See more keywords
Identification and characterization of Orf virus 050 protein proteolysis
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DOI: 10.1007/s11262-017-1430-6
Abstract: The Orf virus 050 (ORFV050) gene is located in the core region of the ORFV genome. It is similar to Vaccinia virus (VV) Copenhagen L4R, and encodes the DNA-binding virion core protein VP8, which has… read more here.
Keywords: protein; proteolysis; orf virus; virus 050 ... See more keywords
Changes of Arg-X proteolysis localization under conditions of deacetylation inhibition of nuclear proteins in spring and winter wheat seedlings
Sign Up to like & getrecommendations! Published in 2018 at "Acta Physiologiae Plantarum"
DOI: 10.1007/s11738-018-2652-5
Abstract: The investigation of the nuclear proteins has always been relevant, because they are involved in the expression, replication, storage, reparation and transmission of genetic information. It is known that sodium butyrate, as an inhibitor of… read more here.
Keywords: proteolysis; winter wheat; nuclear proteins; deacetylation inhibition ... See more keywords
In-tip nanoreactors for cancer cells proteome profiling.
Sign Up to like & getrecommendations! Published in 2017 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2016.11.021
Abstract: Mass spectrometry (MS)-based proteome profiling is essential for molecular diagnostics in modern biomedical study. To date, sample preparation including protein extraction and proteolysis is still very challenging and lack of efficiency. Recently tips-based sample preparation… read more here.
Keywords: proteolysis; cancer cells; proteome profiling; sample preparation ... See more keywords
Investigation of Methionine Sulfoxide Formation as a Regulator of Proteolysis
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DOI: 10.1016/j.bpj.2016.11.1117
Abstract: The oxidation status of the methionine in the Tyr-Met cleavage site of von Willebrand Factor affects its rate of proteolysis and therefore oxidation has been proposed as a potential regulator of coagulation. More generally, little… read more here.
Keywords: proteolysis; oxidation; cleavage; methionine ... See more keywords
Laser-light backscattering response to water content and proteolysis in dry-cured ham
Sign Up to like & getrecommendations! Published in 2017 at "Food Control"
DOI: 10.1016/j.foodcont.2017.02.001
Abstract: Abstract Laser backscattering imaging (LBI) is a low-cost technology proposed to determine non-invasively composition and microstructural characteristics of agro food and dairy products. The aim of this work was to define the effect of different… read more here.
Keywords: cured ham; proteolysis; laser; water content ... See more keywords
Proteolysis in Danish blue cheese during ripening
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DOI: 10.1016/j.idairyj.2019.05.017
Abstract: Abstract Proteolysis in Danish blue cheese was studied during 9 weeks’ ripening. Levels of pH 4.6-soluble N as a percentage of total N increased from 7.2% to 25%, indicating extensive proteolysis. Urea-polyacrylamide gel electrophoretograms confirmed… read more here.
Keywords: proteolysis danish; blue cheese; proteolysis; danish blue ... See more keywords
Proteomic footprint of ultrasound intensification on sliced dry-cured ham subjected to mild thermal conditions.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2018.10.002
Abstract: Ultrasound can intensify the heating process used to correct texture defects in dry-cured hams. The effect of ultrasound-assisted heating on the proteome of sliced dry-cured ham was evaluated. Dry-cured hams with high proteolysis index (PI > 36)… read more here.
Keywords: cured ham; proteolysis; proteomic footprint; sliced dry ... See more keywords