Measuring protein structural changes on a proteome-wide scale using limited proteolysis-coupled mass spectrometry
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DOI: 10.1038/nprot.2017.100
Abstract: Protein structural changes induced by external perturbations or internal cues can profoundly influence protein activity and thus modulate cellular physiology. A number of biophysical approaches are available to probe protein structural changes, but these are… read more here.
Keywords: structural changes; mass spectrometry; proteolysis coupled; protein structural ... See more keywords