Systematic analysis of alterations in the ubiquitin proteolysis system reveals its contribution to driver mutations in cancer
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DOI: 10.1038/s43018-019-0001-2
Abstract: E3 ligases and degrons, the sequences they recognize in target proteins, are key parts of the ubiquitin-mediated proteolysis system. There are several examples of alterations of these two components of the system that have a… read more here.
Keywords: cancer; driver mutations; system; proteolysis system ... See more keywords